Most of the targets tonight were hard ones like buildings, a senior US official tells Jim Acosta.
The strike started with Tomahawk missile strikes from sea, then bombers and fighters went in, a senior US military official told Jim Sciutto. Strikes continue this hour.
Tonight the intention is to have an initial, definitive blow, the official said. Major targets were on the list and the pace is intense.
Over the coming days, will see more of a pace similar to how it has unfolded in Iraq.
The U.S. is the only non-Arab nations taking part. The others are Saudi Arabia, UAE and Jordan
Diplomatic sources tell Elise Labott that alongside US, Jordan, Saudi Arabia and the UAE, Bahrain is also taking part in the airstrikes. That makes 5 nations
Sr US military official: Targets are meant to get to ISIS' ability to command, control, resupply and deploy
Another nation: Qatar was also involved, though not clear if they actually conducted strikes, diplomatic source tell CNN's Elise Labott
This is the reaction CNN's Jim Sciutto received from the Free Syrian foreign missionr: "Quote Syrian opposition adviser: "Thank God, thank God. What a momentous day-- a day that we have been looking forward to for so so long. It's a big step forward, but we are nonetheless clear eyed that it will be a prolonged campaign to defeat ISIS. There's a great deal of work to do ahead; there will be operational coordination between the Syrian opposition and the United States as the military strikes move forward."
While law enforcement officials are aware the Syria strikes could incite a response inside the U.S., there's no evidence anything is in the works. That's according to a U.S. official to CNN's Pam Brown.
Guests James Reese, Rick Francona, and Mark Hertling react to the United States commencing airstrikes on ISIS in Syria
Multiple targets hit in Raqqa: